Abstract
BACKGROUND: Right-sided infective endocarditis is uncommon, and isolated pulmonic valve infective endocarditis (PVIE) is rare. Chronic haemodialysis is a risk factor for developing infective endocarditis. but recurrent PVIE in this population is not well described. CASE SUMMARY: A 32-year-old male with end-stage renal disease on chronic haemodialysis and diagnosed with PVIE 6 months back due to Staphylococcus epidermidis without identified source of infection presented again with recurrent PVIE with methicillin sensitive S. aureus, new pulmonic septic emboli, and peri-graft fluid collection on imaging, which was explanted with negative follow-up culture. DISCUSSION: Through this index case, we describe the unique pathology of recurrent isolated PVIE and explore its diagnostic and management considerations.