Lectin staining patterns in human gastric mucosae with and without exposure to Helicobacter pylori

幽门螺杆菌感染与否对人胃黏膜凝集素染色模式的影响

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Abstract

The aim of the present study was to evaluate qualitative changes in the glycoconjugate expression in human gastric tissue of positive and negative patients for Helicobacter pylori, through lectins: Wheat Germ Agglutinin (WGA) and Concanavalin A (Con A). The lectins recognized differently the glycoconjugates in the superficial mucous layer at the gastric tissues. The results suggest a significant change in the carbohydrate moieties present on the surface of the gastric cells during infection.

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