The marmoset monkey: a multi-purpose preclinical and translational model of human biology and disease

狨猴:一种用于研究人类生物学和疾病的多用途临床前和转化模型

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Abstract

The development of biologic molecules (monoclonal antibodies, cytokines, soluble receptors) as specific therapeutics for human disease creates a need for animal models in which safety and efficacy can be tested. Models in lower animal species are precluded when the reagents fail to recognize their targets, which is often the case in rats and mice. In this Feature article we will highlight the common marmoset, a small-bodied nonhuman primate (NHP), as a useful model in biomedical and preclinical translational research.

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