Digger: directed annotation of immunoglobulin and T cell receptor V, D, and J gene sequences and assemblies

Digger:免疫球蛋白和T细胞受体V、D和J基因序列及组装的定向注释

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Abstract

SUMMARY: Knowledge of immunoglobulin and T cell receptor encoding genes is derived from high-quality genomic sequencing. High-throughput sequencing is delivering large volumes of data, and precise, high-throughput approaches to annotation are needed. Digger is an automated tool that identifies coding and regulatory regions of these genes, with results comparable to those obtained by current expert curational methods. AVAILABILITY AND IMPLEMENTATION: Digger is published under open source license at https://github.com/williamdlees/Digger and is available as a Python package and a Docker container.

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