Plasma phospholipid fatty acid concentration and incident coronary heart disease in men and women: the EPIC-Norfolk prospective study

男性和女性血浆磷脂脂肪酸浓度与冠心病发病率:EPIC-Norfolk 前瞻性研究

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作者:Kay-Tee Khaw, Marlin D Friesen, Elio Riboli, Robert Luben, Nicholas Wareham

Background

The lack of association found in several cohort studies between dietary saturated fat and coronary heart disease (CHD) risk has renewed debate over the link between dietary fats and CHD.

Conclusions

In this study, plasma concentrations of even chain saturated PFA were found to be positively and omega-6 polyunsaturated PFA inversely related to subsequent coronary heart disease risk. These findings are consistent with accumulating evidence suggesting a protective role of omega-6 fats substituting for saturated fats for CHD prevention.

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