Abstract
Donovanosis is a chronic granulomatous ulcerative sexually transmitted infection caused by Klebsiella (Calymmatobacterium) granulomatis. A 39-year-old female patient with underlying HIV infection presented to the department of dermatology outpatient department with a painless ulcer over the left labia majora for 3 months. Histopathological examination revealed histiocyte which contains granular material resembling coccobacilli and Giemsa staining was positive for Donovan bodies. She was treated with doxycycline 100 mg twice daily and azithromycin 1 g once weekly for 3 weeks and further azithromycin 1 g weekly for the next 9 weeks till complete healing of the lesion. Due to the rarity of this condition in our region, we present this case of donovanosis in an HIV-positive female patient.