Basal cell carcinoma arising in a sebaceous naevus

起源于皮脂腺痣的基底细胞癌

阅读:1

Abstract

Sebaceous naevus is a rare non-melanocytic congenital skin hamartoma. Even more rare is the transformation of these lesions into malignant skin cancers, most notably basal cell carcinomas (BCCs). We discuss a case in an adult with later malignant transformation into BCC reported by clinical pathologists. There is dispute about the accurate incidence of malignant transformation. More recently, research has shown that transformation into BCC is unlikely, in that the origins of these lesions arise in trichoblastoma. Evidence from this comes from the changes in mutation pathways that are distinctly separate. A consensus between dermatology, plastic surgery and clinical pathologists is beneficial to decide the best management for these individuals. The limiting factor is the agreement of diagnosis, compounded with conflicting large series multi-centre trials to determine the likelihood of transformation. We feel that each case should be managed individually taking into account patient and/or parent preference with the surgeon offering advice to help the patient guide management decisions. Patient/parent education is important and long-term follow-up by plastic surgeons or dermatologists is highly recommended.

特别声明

1、本页面内容包含部分的内容是基于公开信息的合理引用;引用内容仅为补充信息,不代表本站立场。

2、若认为本页面引用内容涉及侵权,请及时与本站联系,我们将第一时间处理。

3、其他媒体/个人如需使用本页面原创内容,需注明“来源:[生知库]”并获得授权;使用引用内容的,需自行联系原作者获得许可。

4、投稿及合作请联系:info@biocloudy.com。