Abstract
INTRODUCTION: Aesthetic gynecology procedures have been gaining growing interest among patients seeking improvement in the appearance, elasticity, and hydration of the external genitalia. A rising number of individuals attending aesthetic dermatology clinics request minimally invasive treatment options to enhance the quality of genital skin. This study presents preliminary findings on a novel formulation for chemical biostimulation of labial skin, designed to improve tissue firmness and structural integrity. METHODS: A pilot study was conducted to assess the clinical outcomes of a chemical biostimulation protocol performed on the external genital area. The primary endpoints were improvement in skin tension and thickness. High-frequency ultrasound imaging was employed as a quantitative tool for evaluating tissue hydration. RESULTS: The treatment protocol led to a visible enhancement in tissue firmness and hydration. No significant effect was observed in relation to skin pigmentation. High-frequency ultrasound provided consistent and reliable measurements of tissue hydration, confirming its usefulness as an objective assessment method in aesthetic gynecology. DISCUSSION: The pilot data support the potential of chemical biostimulation as a minimally invasive option for improving genital skin quality. Furthermore, high-frequency ultrasound appears to be a valuable adjunct in the objective evaluation of treatment effects. These preliminary results warrant further investigation in larger clinical trials.