Efficacy of 532-nm Q-switched Nd:YAG Laser in the Treatment of Lip Melanosis

532纳米Q开关Nd:YAG激光治疗唇部黑变病的疗效

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Abstract

INTRODUCTION: Lip pigmentation is frequently encountered in the Dermatology outpatient department. No effective treatment is available so far. Topical treatment requires longer time and is often unsatisfactory. AIM: The aim of this work was to study the efficacy of 532-nm Q-switched Nd:YAG laser in the treatment of lip melanosis. SETTINGS AND DESIGN: This was a prospective interventional study. MATERIALS AND METHODS: Twenty patients in the age group 27-53 years were included in the study. Eight patients had diffuse pigmentation and twelve patients had focal pigmentation. Test spot was done. After topical anesthesia, Q-switched Nd:YAG laser was used. Treatment interval was 4 weeks. Follow-up was done at 1 week and then monthly. STATISTICAL ANALYSIS USED: Wilcoxon signed ranks test and P value. RESULTS: Seven patients (35%) showed an excellent response with more than 75% of pigment clearance. Seven patients (35%) showed a good response, two patients (10%) moderate response, and two patients (10%) had a mild response. Two patients had recurrence after 3 months follow-up. The average number of sessions required for clearance of pigmentation was 2.5. No scarring was seen. CONCLUSION: 532-nm Q-switched Nd:YAG laser is safe and effective in the management of lip pigmentation and gives rapid results.

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