Abstract
BACKGROUND: Platelet-rich plasma (PRP) is an integral biotherapeutic modality with evolving significance in the medical domain. Despite its expanding applications, a comprehensive bibliometric evaluation is essential to understand its development and impact. METHODS: The Web of Science core collection subject search identified articles pertinent to PRP applications. Analytical tools, including CiteSpace, VOSviewer, Bibliometrix (R-Tool for R-Studio), TBtools, SCImago Graphica, Origin, and Excel, facilitated the bibliometric scrutiny. This examination spanned dimensions ranging from geographical and institutional contributions to thematic shifts and keyword prevalence. RESULTS: A corpus of 5167 publications was analyzed, with the United States, particularly the Hospital for Special Surgery, emerging as major contributors. The American Journal of Sports Medicine was identified as the primary journal, and Anitua Eduardo as the leading author in the domain. Keyword analysis highlighted evolving research themes, with a shift from traditional applications in orthopedics and dentistry to emerging areas such as dermatology, aesthetics, and chronic pain management. CONCLUSION: The bibliometric analysis of PRP research reveals a multifaceted array of applications across various medical disciplines and highlights areas requiring further exploration, particularly in standardization, personalization, and safety. Future advancements in PRP research will necessitate innovative exploration, ethical considerations, and rigorous scientific validation to fully harness the therapeutic potential of PRP and related therapies.