Abstract
Extrusion printing based on biocompatible filaments offers a wide variety of targeted medical and dental applications in the area of personalized medicine, if combined with bioactive nanomaterials. However, this requires filament to be coated with bioactive nanomaterial. This study introduces a concept of a machine to coat filament with bioactive nanomaterials and its application. A machine was constructed with modules manufactured using additive manufacturing. A filament spool of polylactide (PLA) or glycol-modified polyethylene terephthalate (PETG) was transported through a copper tube, with the outer surface of the filament heated to the appropriate glass transition temperature to incorporate added nanomaterials such as nano-hydroxyapatite (nHA) or nano-fluorapatite(nFA). Coatings with nHA led to an increase in diameter of around 3 μm, while coatings with nFA increased the diameter by 4 μm. Printing of cubes with a standard extrusion printer platform using PLA or PETG filaments with added nHA or nFA has been successfully carried out. Scanning electron microscope (SEM) images of coated filaments and printed cubes showed an irregular distribution of nHA or nFA, which could be verified by energy dispersive X-ray analysis (EDX). Adding and adjusting bioactive nanomaterials to filament with a coating machine for filament proved to generate printable filaments. With the wide range of possible applications by different nanomaterials it is anticipated that extrusion printing can cover needs for personalized medicine and dentistry.