Abstract
In this review, applications of engineered peptide nanomaterials in enhanced cancer imaging are summarized, focusing on the most pertinent of reports. The design principles of said peptide nanostructures are outlined as well as their functionalization for imaging modalities and tumor targeting. The landscape of the field is explored and areas that were deemed underdeveloped are highlighted. Finally, the challenges and limitations that must be overcome to enable the wider clinical adoption of peptide-based nanomaterials in cancer imaging are discussed, and future perspectives are offered.