Abstract
With the rising prevalence of obesity worldwide, the condition and its associated complications have become a significant public health challenge. The emergence of nanotechnology presents new opportunities for obesity treatment by enabling the design and manipulation of materials at the nanoscale to exhibit unique physicochemical properties, targeted delivery capabilities, and multifunctional therapeutic effects. This review systematically explores recent advances in nanotechnology-based strategies for obesity management, focusing on the pathological characteristics of obesity, the types of nanomaterials for the treatment, and the therapeutic strategies provided by nanotechnology. Furthermore, the review critically examines translational challenges while proposing innovative solutions. This work aims to foster the effective application and rapid advancement of nanotechnology in addressing obesity.