Eosinophilic Esophagitis Secondary to Sublingual Immunotherapy Using the Aeroallergen Timothy Grass Pollen Allergy Extract: A Case Report

使用提摩西草花粉过敏提取物进行舌下免疫疗法引起的嗜酸性食管炎:病例报告

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Abstract

Eosinophilic esophagitis results in a chronic immune-mediated condition of the esophagus characterized by esophageal dysfunction and eosinophil-predominant inflammation. While food-based oral immunity therapy (OIT) is a recognized trigger for eosinophilic esophagitis, the impact of sublingual immunotherapy (SLIT) for aeroallergens is less well established. We present an unusual case of eosinophilic esophagitis in a 14-year-old male induced by SLIT and resolved after discontinuing SLIT with Timothy grass pollen allergy extract (GRASTEK®, ALK-Abelló, Inc., Bedminster, USA), which, to our knowledge, has not been previously reported.

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