Galenic dural arteriovenous fistula in neurofibromatosis type 1 treated with Onyx

神经纤维瘤病 1 型合并 Galenic 硬脑膜动静脉瘘,采用 Onyx 治疗

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Abstract

Galenic dural arteriovenous fistula (GDAVF) represents a unique, hard-to-treat subgroup of tentorial dural arteriovenous fistulae. Neurofibromatosis type 1 (NF1) has been infrequently associated with different cerebrovascular conditions that may lead to either ischemic or haemorrhagic stroke. Intracranial GDAVF has not been described in NF1 patients. We present an unusual case of GDAVF in a 37-year-old man with NF1. The fistula drained directly to the vein of Galen through multiple feeders. Complete occlusion of the fistula was achieved through trans-arterial embolisation with Onyx (ethylene vinyl alcohol copolymer) in a single treatment session. Deep venous drainage remained intact, and the patient recovered well. To our knowledge, this is the first report on complete closure of GDAVF with NF1 using trans-arterial embolisation. The preservation of functioning of the straight sinus may have contributed to the success of treatment.

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