Cerebral vasospasm and intracerebral haemorrhage in a case of pregnancy-related thrombotic thrombocytopoenic purpura/haemolytic uraemic syndrome

妊娠相关血栓性血小板减少性紫癜/溶血性尿毒综合征病例中出现脑血管痉挛和脑出血

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Abstract

We report a case of a woman with pregnancyrelated thrombotic thrombocytopoenic purpura/haemolytic uraemic syndrome (TTP/HUS) who developed cerebral vasospasm similar to that seen in the other pregnancy-related thrombotic microangiopathic syndromes of eclampsia and HELLP syndrome. A further complication in this case was the development of a focal intracerebral haemorrhage necessitating surgical removal. Despite a successful evacuation of the haematoma and several plasma exchange treatments she developed recurrent haemolysis and thrombocytopoenia with an eventual fatal outcome due to severe pulmonary and gastrointestinal haemorrhage.

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