Abstract
Epigenetics has long been a hot topic in the field of scientific research. The scope of epigenetics usually includes chromatin remodelling, DNA methylation, histone modifications, non-coding RNAs and RNA modifications. In recent years, RNA modifications have emerged as important regulators in a variety of physiological processes and in disease progression, especially in human cancers. Among the various RNA modifications, m(6) A is the most common. The function of m(6) A modifications is mainly regulated by 3 types of proteins: m(6) A methyltransferases (writers), m(6) A demethylases (erasers) and m(6) A-binding proteins (readers). In this review, we focus on RNA m(6) A modification and its relationship with urological cancers, particularly focusing on its roles and potential clinical applications.