Abstract
BACKGROUND: Frailty is a state of high vulnerability to adverse health outcomes. It is an important factor influencing the prognosis of older, critically ill patients. Several methods to assess frailty were evaluated in the critical care setting. The Pictorial Fit-Frail Scale (PFFS) is a validated quick and easy-to-use tool for frailty assessment. It takes < 5 min to fill by the patient or caregiver; it requires no clinical examination by medical staff. This study evaluated the use of the PFFS in an intensive care unit (ICU). METHODS: A single-center retrospective study, performed in an 18-bed mixed medical-surgical ICU in a university-affiliated tertiary hospital. As of 1/9/2022, all older patients are routinely asked to fill out the PFFS. Patients were grouped based on their PFFS score. Baseline characteristics and admission outcomes were compared. Correlation between the PFFS and prognostic scores was examined. Mortality was analyzed using logistic and Cox regressions. RESULTS: 168 patients were included. 56 (33.33%) patients were non-frail, 81 (48.21%) were mildly-moderately frail, and 31 (18.45%) were severely frail. There were no differences in baseline characteristics or prognostic scores between frailty groups. No correlation was found between PFFS, age, APACHE2, and SOFA24. Multivariate logistic regression demonstrated an association between frailty and 90d but not with ICU mortality. Cox regression demonstrated higher mortality in the mild-moderate frailty (HR 2.053, 95%CI 1.009, 4.179) and severe frailty (HR 4.353, (95% CI 1.934, 9.801)) groups compared to the non-frail group. CONCLUSION: Frailty assessment by the PFFS in the ICU is feasible. Frailty is a distinct characteristic of older, critically ill patients and is independently associated with 90d mortality.