Detection of carbapenemase producing Acinetobacter baumannii ST19 from Georgia and Ukraine carrying bla (OXA-23), bla (OXA-72), and/or bla (NDM-5), December 2019 to June 2023

2019年12月至2023年6月,在格鲁吉亚和乌克兰检测到携带bla(OXA-23)、bla(OXA-72)和/或bla(NDM-5)的产碳青霉烯酶鲍曼不动杆菌ST19菌株

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Abstract

In 2003-2023, amid 5,436 Acinetobacter baumannii isolates collected globally through the Multidrug-Resistant Organism Repository and Surveillance Network, 97 were ST19PAS, 34 of which carbapenem-resistant. Strains (n = 32) sampled after 2019 harboured either bla (OXA-23), bla (OXA-72), and/or bla (NDM-5). Phylogenetic analysis of the 97 isolates and 11 publicly available ST19 genomes revealed three sub-lineages of carbapenemase-producing isolates from mainly Ukraine and Georgia, including an epidemic clone carrying all three carbapenemase genes. Infection control and global surveillance of carbapenem-resistant A. baumannii remain important.

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