Abstract
Digital transformation of healthcare is rapidly progressing. Digital transformation improves the quality of services and access to health information for users, reduces the workload and associated costs for healthcare providers, and supports clinical decision-making. Data and artificial intelligence (AI) play a key role in this process. The AI used for this purpose is called medical AI. Medical AI is currently undergoing a shift from task-specific to general-purpose models. Large language models have the potential to systematize existing medical knowledge in a standardized way. The usage of AI in medicine is not limited to digital transformation; it plays a pivotal role in fundamentally changing the state of medical science. This approach, known as "AI for Medical Science," focuses on pioneering a form of medical science that predicts the onset and progression of disease based on the underlying causes of disease. The key to such predictive medicine is the concept of "states," which can be sought through machine learning. Using states instead of symptoms not only dramatically improves the accuracy of identification (diagnosis) and prediction (prognosis) but also potentially pioneers P4 medicine by integrating it with empirical knowledge and theories based on natural principles.