Abstract
Perivascular epithelioid cell tumors (PEComas) are rare mesenchymal tumors that tend to occur in multiple organs and the biological behavior of it between benign and malignant. They are even less common in the liver and there is still no effective treatment method established. In particular, how to deal with it when the imaging manifestations of the lesion are predominantly giant cystic are a question that we need to investigate. We present PEComas in two female patients with large cystic-solid lesions on ultrasound with clinical signs of nonspecific pain and a large mass in the right upper quadrant. Both patients underwent contrast-enhanced ultrasound (CEUS) and interventional ultrasound to assist in diagnosis and treatment. Depending on the patient's condition, we take a different approach to treatment. To our knowledge, such reports have never been documented before.