Abstract
Myopericytomas (MPCs) are a rare type of benign, perivascular, soft tissue tumor. The intravascular subtype of this tumor is particularly rare, with <200 cases reported in the literature. This case report describes the diagnosis and surgical management of a popliteal fossa intravascular subtype of MPC in a 77-year-old man presenting with claudication and a mass behind the knee. After months of extensive diagnostic workup, excisional biopsy both confirmed the diagnosis and resolved his symptoms. This report highlights how highly vascularized soft tissue masses can present extensive diagnostic uncertainty and operative complexity.