Spinal teratoma in an adolescent: a rare case report with intradural presentation and review of management strategies

青少年脊髓畸胎瘤:一例罕见的硬膜内表现病例报告及治疗策略回顾

阅读:1

Abstract

INTRODUCTION: Spinal teratomas are rare tumors of pluripotent germ cells, accounting for <0.5% of all spinal cord tumors and 2% of all teratomas. While they commonly occur in gonads, extragonadal spinal presentation is uncommon. They are often associated with spinal dysraphism and present variably depending on tumor location and neural compression. MRI aids in diagnosis, but histopathological examination remains the gold standard. Early detection is vital to avoid irreversible neurological damage. CASE PRESENTATION: A 16-year-old Indian male presented with progressive lower back pain for one year, followed by involuntary micturition and bilateral temporal headaches for six months. Neurological examination was normal, but persistent urinary symptoms warranted imaging. MRI revealed an intradural lesion at D11-L1, consistent with a spinal teratoma. The patient underwent surgical excision, and histopathology confirmed a monodermal teratoma. At three-month follow-up, the patient's symptoms had completely resolved. DISCUSSION: Spinal teratomas may be classified as mature, immature, or malignant. Mature teratomas are most common in adults. Theories regarding their origin include misplaced primordial germ cells and dysembryogenic malformations. Clinical presentation varies from pain to autonomic dysfunction, demanding high clinical suspicion and prompt imaging. Surgical excision remains the mainstay of treatment. Subtotal resection is considered when tumors adhere to critical neural structures. Although rare, recurrence, malignant transformation, and aseptic meningitis have been reported, emphasizing the need for long-term follow-up. CONCLUSION: This case underscores the importance of early neuroimaging in patients with atypical spinal symptoms. Surgical resection is definitive, while histopathology confirms the diagnosis. Regular follow-up remains essential.

特别声明

1、本页面内容包含部分的内容是基于公开信息的合理引用;引用内容仅为补充信息,不代表本站立场。

2、若认为本页面引用内容涉及侵权,请及时与本站联系,我们将第一时间处理。

3、其他媒体/个人如需使用本页面原创内容,需注明“来源:[生知库]”并获得授权;使用引用内容的,需自行联系原作者获得许可。

4、投稿及合作请联系:info@biocloudy.com。