Abstract
RATIONALE: Primary hepatic neuroendocrine tumors are extremely rare tumors originating from neuroendocrine cells. Due to the lack of neuroendocrine symptoms and specific imaging features, diagnosis is also challenging. PATIENT CONCERNS: An elderly woman's physical examination revealed a liver mass that had been present for 3 months. The patient presented with diffuse liver lesions deemed unresectable at the time of diagnosis. Interventional and chemotherapy treatment was performed after performing puncture pathology. However, the outcomes were unsatisfactory. This article reports a case of primary hepatic neuroendocrine tumor. DIAGNOSES: The pathological diagnosis was hepatic neuroendocrine tumor (G2 grade). INTERVENTIONS: Implement CAPTEM combined with TACE treatment for patients. OUTCOMES: CAPTEM combined with TACE treatment was ineffective. The patient eventually lost access. LESSONS: Primary hepatic neuroendocrine tumor surgical resection to obtain pathology is currently the best way for treatment and diagnosis. And call for the establishment of its own grading treatment guidelines, which are very important for evaluating the malignancy and prognosis of tumors.