Abstract
Adrenocortical nodular hyperplasia and gastrointestinal stromal tumors are rare conditions, and their simultaneous occurrence in a single patient poses diagnostic and therapeutic challenges. Here, we present the case of a 39-year-old female patient who underwent surgical resection for concurrent adrenocortical nodular hyperplasia and GIST on the posterior part of the gastric fundus. The patient presented with symptoms of hyperaldosteronism and malignant hypertension, leading to the discovery of these two distinct tumors. Preoperative evaluation revealed normal laboratory findings and hormone levels, except for hyperaldosteronism and hypertension. The surgical intervention included left suprarenal gland removal and wedge resection of the gastric tumor. The patient experienced a successful outcome without intraoperative complications and remained normotensive during follow-up visits, with sustaining hormonal balance. This case underscores the importance of multidisciplinary collaboration and tailored surgical planning in managing complex neoplastic conditions.