Abstract
Oxalis corniculata L. (O. corniculata) has attracted increasing attention as a natural source of antioxidants with diverse pharmacological potential. Phytochemical studies have identified a diverse spectrum of metabolites, dominated by flavonoids, polysaccharides, and organic acids. These compounds exhibit antioxidant properties as well as related biological activities, including anti-inflammatory, antimicrobial, neuroprotective, hypoglycemic, and anticancer effects. Its long-standing use in traditional remedies, along with its incorporation into approved Chinese patent medicines, underscores its safety and translational value. This review synthesizes recent advances in the chemical composition, bioactivities, and molecular mechanisms of O. corniculata, emphasizing its antioxidant-driven pharmacological prospects. The review highlights O. corniculata as a sustainable and accessible botanical resource with significant potential for the development of pharmaceuticals, dietary supplements, and health-promoting applications.