Abstract
OBJECTIVES: The analgesic and anti-inflammatory effects of methanolic extract of Limnophila repens (MELR) were assessed at 200 and 400 mg/kg. MATERIALS AND METHODS: In carrageenan-mediated paw edema, the anti-inflammatory effect of MELR was investigated and analgesic activity was assessed by central and peripheral models. RESULTS: MELR had strong analgesic and anti-inflammatory effects at different dosages (200 and 400 mg/kg). The study results confirmed the use of Limnophila as both an analgesic and anti-inflammatory. The strong anti-inflammatory and analgesic effects can be caused by anabolic steroids, i.e. β-sitosterol and stigmasterol; and flavonoids, i.e. quercetin and glycosides, in the extraction of some kind of inflamed arbitrators. CONCLUSION: Based on the study, we can conclude that Limnophila repens had analgesic and anti-inflammatory activity. In addition to organic studies, however, additional phytochemicals are required to evaluate the extra energetic chemicals responsible for the antinociceptive and anti-inflammatory effects.