Ruminant globin gene structures suggest an evolutionary role for Alu-type repeats

反刍动物珠蛋白基因结构表明Alu型重复序列在进化中发挥作用

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Abstract

Bovine fetal and adult globin genes were cloned and subjected to DNA sequence analysis. Both of these genes contained insertions of Alu-type repetitive DNA within their introns. Comparison of cow and goat beta-type globin genes indicates that intragenic DNA insertions played a role in their evolution. These data support the theory that Alu-type repeats maintain genetic diversity by inhibiting gene conversion.

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