The emerging roles of N6-methyladenosine (m6A)-modified long non-coding RNAs in human cancers

N6-甲基腺苷(m6A)修饰的长链非编码RNA在人类癌症中的新兴作用

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Abstract

N(6)-methyladenosine (m(6)A) epitranscriptional modifications widely exist in RNA, which play critical roles in RNA metabolism and biogenesis processes. Long non-coding RNAs (lncRNAs) are class of non-coding RNAs longer than 200 nucleotides without protein-coding ability. LncRNAs participate in a large number of vital biological progressions. With the great improvement of molecular biology, m(6)A and lncRNAs are attracting more attention from researchers and scholars. In this review, we overview the current status of m(6)A and lncRNAs based on the latest research, and propose some viewpoints for future research perspectives.

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