Steroid administration facilitates recovery in severe refractory Bell's palsy patients who did not receive steroids in the acute stage: a retrospective study

回顾性研究表明,对于急性期未接受类固醇治疗的重度难治性贝尔氏麻痹患者,类固醇治疗可促进其康复。

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Abstract

BACKGROUND: In the present study, we aimed to evaluate the efficacy of steroid treatment on patients with severe refractory Bell's palsy in the recovery stage who had not been treated with steroids in the acute stage. METHODS: We performed a retrospective analysis of 122 patients with severe refractory Bell's palsy. These patients had a clinical course of 15-30 days, House-Brackmann (HB) grade ≥ IV, and no history of steroid therapy. Of those, 65 patients who received steroid therapy after hospitalization were assigned to the steroid group and 57 patients who did not receive steroid therapy were assigned to the control group. Both groups received folic acid and mecobalamin, acupuncture, and mirror exercises as basic treatments. The primary outcome was the rate of grade I on the HB Grading Scale. The secondary outcome was the Sunnybrook Facial Grading system. All outcomes were assessed before treatment (baseline), at 2 weeks of steroids treatment (2 weeks), and at 8 weeks after steroids treatment (10 weeks). RESULTS: The steroid group had a better recovery rate of facial-nerve function than the control group (p < 0.05). CONCLUSION: The use of steroids facilitate the recovery of severe refractory Bell's palsy in the recovery stage, who did not receive steroids in the acute stage.

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