Chemical Review of Gorgostane-Type Steroids Isolated from Marine Organisms and Their (13)C-NMR Spectroscopic Data Characteristics

海洋生物中分离得到的戈尔戈斯坦型甾类化合物的化学综述及其<sup>13</sup>C-NMR光谱数据特征

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Abstract

Gorgostane steroids are isolated from marine organisms and consist of 30 carbon atoms with a characteristic cyclopropane moiety. From the pioneering results to the end of 2021, isolation, biosynthesis, and structural elucidation using (13)C-NMR will be used. Overall, 75 compounds are categorized into five major groups: gorgost-5-ene, 5,6-epoxygorgostane, 5,6-dihydroxygorgostane, 9,11-secogorgostane, and 23-demethylgorgostane, in addition to miscellaneous gorgostane. The structural diversity, selectivity for marine organisms, and biological effects of gorgostane steroids have generated considerable interest in the field of drug discovery research.

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