Gastroduodenal perforation in preterm babies treated with dexamethasone for bronchopulmonary dysplasia

接受地塞米松治疗支气管肺发育不良的早产儿发生胃十二指肠穿孔

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Abstract

Three cases of gastroduodenal perforation and one case of ulceration and extreme thinning of the gastric wall occurred in preterm babies treated with dexamethasone for bronchopulmonary dysplasia. This complication of treatment with steroids has not to our knowledge previously been described in preterm infants. Urgent abdominal paracentesis was an essential part of the resuscitation in these cases, and this potentially serious side effect should be considered in all babies treated with steroids.

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