Lymphocytic interstitial pneumonia associated with common variable immunodeficiency resolved with intravenous immunoglobulins

与常见变异型免疫缺陷相关的淋巴细胞性间质性肺炎经静脉注射免疫球蛋白治疗后缓解

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Abstract

Lymphocytic interstitial pneumonia (LIP) is a rare form of interstitial lung disease. A few case reports have described an association with common variable immunodeficiency (CVID). Corticosteroids are usually used to treat symptomatic patients but their efficacy has never been studied in a controlled trial. We describe a patient with LIP and CVID who was treated monthly with intravenous immunoglobulins (IVIG) without steroids. The patient improved dramatically. We believe that, in selected cases of LIP and immunodeficiency, IVIG given monthly should be considered as the only treatment without adding steroids.

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