Intra-articular hyaluronic acid is superior to steroids in knee osteoarthritis: A comparative, randomized study

关节内注射透明质酸治疗膝骨关节炎优于类固醇:一项比较性随机研究

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Abstract

BACKGROUND: To compare the short and mid-term results of intraarticular triamcinolone hexacetonide and hyaluronic acid (HA) in knee osteoarthritis. METHODS: A prospective randomized study including 40 patients in steroid and 42 patients in HA group. The outcome was evaluated with Knee Society Score (KSS) and Visual Analog Scale (VAS). RESULT: On KSS function and VAS score, there was no difference till four weeks. On KSS pain there was no difference till 12 weeks (P > 0.05) after that score of steroid group deteriorated rapidly. At six months HA was significantly better than a steroid. CONCLUSION: The HA seems to be better for pain relief and functionality in the short and mid-term periods.

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