Abstract
This study comparing the different parameters of children suffering from multisystem inflammatory syndrome in children (MIS-C) in Kolkata, India, during the two waves (July, 2020-January, 2021 and April-July, 2021) showed that the second wave had a higher propensity of Kawasaki disease (KD)-like presentation, cardiac affection and pediatric intensive care unit admission, and increased incidence of use of steroids for treatment.