Fahr's syndrome: Evaluation of bilateral basal ganglia and calcifications in other brain regions: A report of 3 cases

法尔氏综合征:双侧基底节及其他脑区钙化评估:3例报告

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Abstract

Fahr's syndrome is a rare neurological disorder characterized by abnormal intracranial calcifications, most commonly affecting the basal ganglia. We report 3 cases-2 females aged 71 and 72, and 1 male aged 47-who were incidentally found to have bilateral basal ganglia calcifications on brain CT-scans. The first patient had a history of total thyroidectomy and parathyroidectomy; the second had prior psychiatric illness and was evaluated after a motor vehicle accident; the third was undergoing chemotherapy for hepatocellular carcinoma and presented with generalized weakness. Stroke was excluded in all cases, and each patient was discharged in stable condition. These cases highlight the importance of neuroimaging in identifying Fahr's syndrome, especially in atypical presentations, and underscore the need for thorough metabolic and clinical evaluation to guide diagnosis and management.

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