Abstract
It has been hypothesized that increased intracranial pressure (ICP) may cause sick sinus syndrome (SSS) due to its effect on vagal discharge to the heart, resulting in disruption to the sinus cycle, despite age-related degeneration of the sinoatrial node being the most common intrinsic factor leading to sinus node dysfunction. In this case report, a 47-year-old man with unknown medical conditions presented to the emergency department at King Saud Medical City with a four-day history of headache, confusion, and chest pain. He also reported dizziness and lightheaded. Extensive cerebral venous thrombosis (CVT) and SSS were identified. We investigated the SSS etiology and its relation to CVT, concluding that SSS was caused by elevated ICP secondary to CVT.