Abstract
Chlamydophila psittaci is a zoonotic, intracellular bacterium, found in a wide range of birds, and is the causative agent of psittacosis, or avian chlamydiosis (AC). AC, as well as having significant zoonotic potential, causes high mortality in domestic birds, and there is no effective commercial vaccine. The group of Zhou et al. has generated recombinant adenovirus vaccines, which exhibit significant potential for the prophylactic treatment of poultry. Reduction of AC will affect not only the disease and associated mortality, but should also reduce the incidence of the carrier state, and should improve breeding performance in birds. Design and successful vaccine implementation also has the potential to improve human health, by decreasing zoonotic risk and should also reduce the risk of emergence of antibiotic resistant strains.