Abstract
Natural biological materials provide a rich source of inspiration for building high-performance materials with extensive applications. By mimicking their chemical compositions and hierarchical architectures, the past decades have witnessed the rapid development of bioinspired materials. As a very promising biosourced raw material, silk is drawing increasing attention due to excellent mechanical properties, favorable versatility, and good biocompatibility. In this review, we provide an overview of the recent progress in silk-based bioinspired structural and functional materials. We first give a brief introduction of silk, covering its sources, features, extraction, and forms. We then summarize the preparation and application of silk-based materials mimicking four typical biological materials including bone, nacre, skin, and polar bear hair. Finally, we discuss the current challenges and future prospects of this field.