Exploring and Anticipating the Applications of Organic Room-Temperature Phosphorescent Materials in Biomedicine and Dentistry

探索和预测有机室温磷光材料在生物医学和牙科领域的应用

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Abstract

As popular materials, organic room-temperature phosphorescent (RTP) materials have been studied and developed in many fields. RTP materials have the characteristics of a high signal-to-noise ratio (SNR) and high reactive oxygen species (ROS) quantum yield, which can achieve clear bioimaging and efficient ability of anti-tumor and antibacterial, and have received extensive attention from researchers for imaging, tumor therapy, and antibacterial treatment. Moreover, owing to their flexible molecular structures and various synthesis systems and methods, it may be possible to design and synthesize materials according to individual physiologic environments of patients in medical applications, making bioimaging more accurate and greatly improving tumor and bacterial killing rates. So they have great development potential in the medical field. On the basis of introducing the mechanism of RTP materials that emit phosphorescence and generate ROS, this review summarizes the medical applications of RTP materials from three aspects-bioimaging, tumor treatment and antibacterial treatment-to provide a basis for their application in the field of stomatology.

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