Abstract
A 33-year-old man living with advanced HIV with a histologically confirmed diagnosis of Kaposi sarcoma presented during a SARS-CoV-2 outbreak with worsening shortness of breath. He was treated for confirmed SARS CoV-2 infection with minimal symptomatic response, and whilst undergoing KS treatment on the ward developed the rare complication of plastic bronchitis. He had a prolonged hospital admission undergoing treatment for his Kaposi sarcoma and plastic bronchitis whilst being evaluated for concurrent opportunistic infections.