Abstract
RATIONALE: Primary prostate sarcomas are highly malignant tumors characterized by their low incidence and poor prognosis. Due to this rarity, we present a limited number of case series. PATIENT CONCERNS: In this report, we detail the clinical diagnosis, treatment, and prognosis of the last 6 primary prostatic sarcoma cases. DIAGNOSES: The 6 patients, all adults aged between 21 and 51 years, were diagnosed pathologically through needle biopsy or surgical specimens. INTERVENTIONS: All patients underwent chemotherapy. OUTCOMES: At the time of the last follow-up, only 1 patient continued treatment, while the other 5 had succumbed to disease progression. The overall survival time ranged from 3 to 46 months. LESSONS: Primary prostatic sarcoma presents with an insidious onset and rapid progression, lacking standard treatment options and associated with a very poor prognosis. Early detection and timely surgical intervention may improve the cure rate and extend survival time for affected patients.