Abstract
This case report presents an unusual manifestation of Ewing's Sarcoma (EwS) in the distal clavicle of a 32-year-old male. The patient's journey began with an initial misdiagnosis of a shoulder mass as a benign condition, but advanced imaging techniques later uncovered the malignant nature of the lesion. Emphasizing the complexities of managing EwS in atypical locations and in adult patients, this report details the implementation of a neo-adjuvant chemotherapy regimen. The chemotherapy aimed to reduce tumor size and mitigate the spread, preparing for a more effective surgical resection. The subsequent surgical strategy involved a meticulous resection of the distal clavicle, focusing on achieving clear margins while preserving the functional integrity of the shoulder, crucial for the patient's profession. The postoperative phase was marked by a comprehensive rehabilitation program, crucial for recovery and return to occupational activities. This case underscores the importance of early and accurate diagnosis, the effectiveness of a preoperative chemotherapy strategy, and the need for a multidisciplinary approach, including oncological treatment, surgical precision, and rehabilitative care.