Ethanol facilitates hepatitis C virus replication via up-regulation of GW182 and heat shock protein 90 in human hepatoma cells

乙醇通过上调人肝癌细胞中的 GW182 和热休克蛋白 90 促进丙型肝炎病毒复制

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作者:Terence N Bukong, Wei Hou, Karen Kodys, Gyongyi Szabo

Conclusion

Overall, our results suggest that GW182 protein that is linked to miR-122 biogenesis and HSP90, which has been shown to stabilize the RISC, are novel host proteins that regulate HCV infection during alcohol abuse.

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