Abstract
BACKGROUND: This is a single case report of a rare tumour, pancreatic leiomyosarcoma. CASE OUTLINE: A 44-year-old woman presented with a painless epigastric mass, and CT scan showed a cystic lesion of the head of pancreas. An associated epigastric mass was found to be a lipoma. Pancreatoduodenectomy was successfully performed. Pathology revealed leiomyosarcoma of the pancreas. The patient is well and free of disease four years later. DISCUSSION: Leiomyosarcomas of the pancreas can present with abdominal pain, weight loss and abdominal mass. However, a certain number of tumours will be discovered incidentally and may be cystic in nature. This patient had no antecedent history of gallstones or alcohol and underwent a curative resection.