Data on induction of brown/beige adipocytes in mouse retro-orbital adipose tissues

小鼠眶后脂肪组织中棕色/米色脂肪细胞诱导的数据

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作者:Makoto Sugiyama, Masayuki Funaba, Osamu Hashimoto

Abstract

The data presented here are related to the research article entitled "Inducible brown/beige adipocytes in retro-orbital adipose tissues" [1]. Brown and beige adipocytes dissipate stored energy through the generation of heat by using mitochondrial uncoupling protein 1 (Ucp1), which is a mammalian brown/beige adipocyte-specific protein that promotes proton leakage across the inner mitochondrial membrane. Both cells up-regulate Ucp1 expression in response to β-adrenergic receptor activation such as cold exposure. Here, we provide data on induction of Ucp1 positive cells in retro-orbital white adipose tissues (WAT) from cold exposed both male and female mice. The fluctuation of eye surface temperature was monitored during the cold exposure. In addition, distribution of tyrosine hydroxylase positive bundles was observed in the retro-orbital WAT from the mice.

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