Validated 5' nuclease PCR assay for rapid identification of the genus Brucella

经验证的 5' 核酸酶 PCR 检测方法,用于快速鉴定布鲁氏菌属

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Abstract

A real-time, genus-specific 5' nuclease PCR assay for amplification of a 322-bp fragment of the per gene was developed for rapid (<2 h) identification of Brucella spp. from agar plates. The assay, including an internal amplification control (116 bp), identified Brucella strains (n = 23) and did not detect non-Brucella strains (n = 174), indicating its usefulness, particularly for laboratories with stringent quality assurance programs.

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