Molecular Basis of pathogenicity in Helicobacter pylori clinical isolates

幽门螺杆菌临床分离株致病性的分子基础

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作者：Ramis,Ivy Bastos,Fonseca,Tesiê Leopoldo,de Moraes,Ernani Pinho,Fernandes,Márcia Silveira,Mendoza-Sassi,Raul,Rodrigues,Obirajara,Juliano,Carlos Renan Varela,Scaini,Carlos James,da Silva,Pedro Eduardo Almeida
期刊：Journal of Clinical Microbiology影响因子：5.400
时间：2010起止号：2010 Oct;48(10):3776-8
doi：10.1128/JCM.00472-10

Abstract

This study identified pathogenicity genes in 40 Helicobacter pylori clinical isolates. The cagA, vacA, and iceA genes were detected in 65%, 97.5%, and 97.5% of the isolates, respectively. The cagA, iceA1, and vacAs1a/m1 genes were related to erosive gastritis, whereas the vacAs2/m2 and iceA2 genes were associated with enanthematous gastritis.

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