Glutaraldehyde-Crosslinked Bovine Serum Albumin Hydrogels for Efficient Cu(2+), Ni(2+), and Co(2+) Removal from Water

戊二醛交联牛血清白蛋白水凝胶用于高效去除水中的Cu(2+)、Ni(2+)和Co(2+)

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Abstract

Heavy metal contamination remains a critical threat to water quality, particularly in effluents associated with industrial activities such as electroplating. This study presents an exploratory proof of concept for a simplified and low-requirement method to fabricate bovine serum albumin (BSA) hydrogels crosslinked with glutaraldehyde (GA) as protein-based adsorbents for Cu(2+), Ni(2+), and Co(2+) removal. Hydrogel slabs were prepared using BSA concentrations of 20% and 25% (w/v) and GA in the 0.6-1.0% (v/v) range, with formulation adjustments guided by handling and aqueous stability. Swelling behavior was monitored for 23 days, and 0.9% (v/v) GA was selected to balance network expansion with hydrogel consistency. FT-IR confirmed preservation of protein functional groups in the crosslinked network, and TGA/DTG demonstrated multi-step thermal behavior consistent with hydrated protein matrices and a stabilizing effect of increased GA content. Metal removal tests at 50-100 ppm (Cu(2+), Ni(2+)) and 70-100 ppm (Co(2+)) showed rapid removal approaching equilibrium within the first hours and improved performance at higher BSA content, achieving maximum removal percentages of 99.258% for Cu(2+), 80.733% for Ni(2+), and 76.070% for Co(2+). Adsorption behaviors for Cu(2+) and Co(2+) aligned with the Langmuir model, while Ni(2+) was better described by the Freundlich model. Although the scope is intentionally preliminary and limited to controlled synthetic systems, these results support GA-crosslinked BSA hydrogels as promising, easily fabricated adsorbents and establish a foundation for future studies on broader ion selectivity, competitive adsorption, and adsorption-desorption performance.

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