An Australian perspective on clinical, economic and regulatory considerations in emerging nanoparticle therapies for infections

澳大利亚视角下的新兴纳米颗粒感染疗法的临床、经济和监管考量

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Abstract

Antimicrobial resistance (AMR) poses a growing global health threat. Nanomedicine, combined with drug repurposing, may help extend the effective lifespan of current and new antimicrobials. This review, presents an Australian perspective on nanotechnology-based therapies, highlighting scientific and clinical challenges. Early consideration of the potential barriers to market access may help to accelerate research translation, regulatory approval and patient access to nano-antimicrobial (NAM) drugs for resistant pathogens, not only in Australia, but globally.

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